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🧪 The new label, explained

What is 13-OH?

13-OH is a 2026 label term for an alkaloid from the corydalis root — not kratom, and no relation to 7-OH despite the name. Here's what sellers say it is, what the published research says, and where it stands legally. No health claims.

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What it isA label term on corydalis tablets, new in 2026. Sellers describe it as an alkaloid from the Corydalis yanhusuo tuber, related to tetrahydropalmatine (THP)
Source plantCorydalis yanhusuo — Rhizoma Corydalis, a poppy-family plant from China. Not kratom
In published researchWe found no compound by that name in the published research on this root. Position 13 is real chemistry, though: corydaline, a known corydalis alkaloid, is THP with a methyl group at that position
Relation to 7-OHNone beyond the echo. 7-OH (7-hydroxymitragynine) is a kratom alkaloid, federally scheduled in concentrated form since August 2026
Legal statusCorydalis and its alkaloids aren’t federally controlled, and no regulator has acted on 13-OH by name. We know of no state ban as of October 2026
What’s in a given tabletOnly a lab panel can say. Some products print “13-OH” next to 7-OH on the label — and 7-OH is now scheduled

Chemistry, published data and legal status only — no health claims, no dosing guidance, ever.

Botanical illustration of Corydalis yanhusuo — a low plant with finely divided gray-green leaves and a cluster of tubular purple spurred flowers, rising from a small round tuber with fine roots; a detail study shows the tuber cut open to a bright yellow interior beside a single flower in side view.
Corydalis yanhusuo — A low poppy-family plant. The small round tuber below, yellow inside, is the part sold as Rhizoma Corydalis. Illustration.

A new name for an old root

The plant behind 13-OH isn’t new at all. Rhizoma Corydalis — the dried tuber of Corydalis yanhusuo — has centuries in Chinese herbal tradition and years on American supplement shelves. Its chemistry is a family of isoquinoline alkaloids, led by tetrahydropalmatine (THP). What’s new is the label: after the August 2026 federal scheduling of concentrated 7-OH, corydalis tablets started advertising a compound called “13-OH,” described by sellers as a hydroxylated relative of THP.

Here’s the honest state of the evidence: we found no compound published under the name 13-OH in the research on this root. The number isn’t random — position 13 is where corydaline, a well-documented corydalis alkaloid, differs from THP — but a label pointing at real chemistry isn’t the same as a compound with a published identity, let alone published safety data. Until there’s a paper or a lab panel, “13-OH” tells you which plant a product claims to come from, and not much more.

13-OH vs 7-OH: two different molecules

The names rhyme on purpose. The chemistry and the law don’t.

13-OH7-OH
Source plantCorydalis yanhusuo (corydalis root)Mitragyna speciosa (kratom)
Plant familyPoppy (Papaveraceae)Coffee (Rubiaceae)
Chemical classIsoquinoline alkaloid, per sellersIndole alkaloid
Receptor storyCorydalis alkaloids act mainly at dopamine receptors in published dataOpioid-receptor active
In the literatureNo compound published under this nameWell documented
Federal statusNot controlledConcentrated form scheduled, August 2026

Read the label, not the name

Some tablets in this wave print “13-OH” and “7-OH” side by side. Concentrated 7-OH has been federally scheduled since August 2026 (what changed), so a product listing both isn’t a corydalis product with a bonus — it’s a 7-OH product, with everything that now implies. We don’t carry anything that lists 7-OH. A corydalis tablet worth considering names the plant plainly on its ingredient line; anything beyond that is a question for a third-party lab panel.

What we carry in this lane right now is ketaMIND (13-OH) Tablets 3pk 675mg. Label facts only, no effect claims, and no published third-party panel behind it — we won’t pretend otherwise.

13-OH, answered

What is 13-OH?
A label term that started appearing on tablets in 2026. Sellers describe it as an alkaloid from the tuber of Corydalis yanhusuo — the corydalis root, Rhizoma Corydalis — related to that plant’s best-known alkaloid, tetrahydropalmatine (THP). We couldn’t find a compound by that name in the published research on the plant, so treat it as a marketing name rather than a scientific one.
Is 13-OH the same as 7-OH?
No. 7-OH (7-hydroxymitragynine) comes from kratom, a coffee-family tree, and is opioid-receptor active; concentrated 7-OH has been federally scheduled since August 2026. 13-OH, as sellers describe it, comes from corydalis, a poppy-family plant whose alkaloids act mainly at dopamine receptors in published data. The similar name is the only thing they share.
Is 13-OH kratom?
No. It comes from the corydalis root, not from kratom, and it isn’t covered by the kratom-specific federal action or the state kratom bans.
Is 13-OH legal?
Corydalis and its alkaloids aren’t federally controlled substances, no regulator has acted on 13-OH by name, and we know of no state that bans it as of October 2026. Two caveats: laws in this space move quickly, and some products print “13-OH” alongside 7-OH on the label. Concentrated 7-OH is federally scheduled, so a combination product is a different legal question entirely.
Is there safety data on 13-OH?
Not under that name — there’s no published research on a compound called 13-OH. The plant it’s said to come from has a safety record worth knowing: hepatitis cases reported by the CDC in 1993 involving a product labeled as containing THP, a 2022 Massachusetts precautionary bulletin about corydalis in cannabis edibles, and a ProPublica investigation into a corydalis-infused cannabis product in Colorado. Our Rhizoma Corydalis page covers all three. Anyone with liver concerns, or on prescription medication, should talk to a doctor first.
Does ketaMIND contain 13-OH?
ketaMIND’s box lists Rhizoma Corydalis extract and doesn’t mention 13-OH. Like any corydalis tablet, what it contains beyond the label is a question for a lab panel.
Do you sell 13-OH?
We carry corydalis: ketaMIND (13-OH) Tablets 3pk 675mg. We don’t publish a third-party panel for it, so we make no claims beyond what’s printed on the label — and we don’t carry anything that lists 7-OH.

New name, old root, plain answers.

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